I may be mistaken, but isn't the SC250 the same engine as the GTS250? Either way, I just went out on a 35 mile jaunt, mostly rural roads and a quick 1 mile stretch on the Freeway (highway became official freeeway and I exited on the first exit to continue my travels). While the wind noise with the puig windscreen is bad, I rode with earplugs and could really, really see how nice the windscreen works. While I didnt' go faster than 65mph, I also spent most of the trip doing 40-55mph and it was like butter even at 65. My second fill up today and I got 65 and 68 mpg respectively. And, I still have just under 500 total miles on it.
My choice would be the BV350 if I had to do it all over again. Just because.