My touring jacket and mesh jacket are both high-viz. My impression is that incidences of being tailgated and cut off in traffic have dropped significantly with these jackets.
If I was younger and there was still a chance I could be cool I might be reluctant to wear a pulsating color, but that's behind me.
I also use a white helmet for the increased visibility and to reduce the heat gain in the Colorado sunshine.
"When I was younger I was afraid I'd die riding now that I'm old and falling apart, I'm afraid I won't."