I installed a Kryptonite floor anchor in the garage and use the biggest Kryptonite New York chain and lock setup through the back wheel of the Ducati. The anchor requires drilling three holes in the floor and inserting expansion anchors. The assembly is bolted down with countersunk allen bolts and then hard ball bearings are driven into the hex recesses in the bolts. A cover bolts down over everything.
It takes about a half hour to install if you have a hammer drill.
My philosophy is that if you make it difficult enough to steal, they'll look for an easier one.