Most of the shop guys I've talked to say they'll use nothing but tubeless. They claim the weight savings is worth messing with the glue. They also mention the ability to run low tire pressures and say they never ever get flats. Riddle me this though - doesn't the free-roaming sealant you put in there to prevent flats approach the weight of a tube? I had tubeless tires on a road bike one time. I managed 2 flats on my second ride and had to call a friend to come get me. The bike was disabled and unfixable in the field - at least by me. I've had a million tube flats out riding and fixed 'em all with a patch in just a few minutes. This was years ago and technology has surely changed, but I don't plan to ever mess with tubeless again. For the flats, I started using strips between the tire & tube. I was getting goat's head flats every ride and this totally stopped 'em. It adds a little weight, but I'm in this for the workout as much as anything. Given that I can live with a little extra weight. Of course this won't work for the 'must be as light as possible' crowd. I never understood the lengths to which some people go and the money they'll spend to shave an ounce outside of racing, but to each his own.