I'll try........... Ibanez is actually the worlds largest guitar manufacturer. They make everything from about $150.00 on up to around $5,000.00 or so. Quality is generally good, though like most everyone else, you get what you pay for and the $150.00 ones aren't as nice as the $300.00 ones which aren't as nice as the $800.00 ones which..........etc. A fairly safe rule on place of origin: If it is under $1k, it was probably made somewhere outside the USA. Does it make a difference? Well, setting aside the "Buy American" patriot stuff, not really. The main thing is that it's a manufacturer that gives a damn about quality. The difference between a 22 fret and a 24 fret is 2 frets. The designation has to do with how far up the scale the neck goes. Doesn't really make a difference to a beginner and, truth be told, doesn't make a difference to about 90% of guitarists, beginner or expert. Haven't messed with Rocksmith so I'm no help there. I would say that no matter what you do, get a few private lessons to start with. That will at least get you started on the right foot and help you with basic things like how to fret properly, etc. Financially, that Craigslist listing is an OK deal, but nothing real hot. That's about the same price you could buy a similar used rig at a music store. Most stores will take the time to check everything out and some will even offer a bit of warranty on used gear. That's something you aren't getting with the CL deal. Just something to consider.